Enjoy Free Fast Shipping!
Enjoy Free Fast Shipping!
kratom leaves

Understanding Mitragynine Extraction

Open Sidebar

Mitragynine is a fascinating alkaloid found in Mitragyna speciosa, commonly known as kratom. As one of the two main compounds found in Kratom, mitragynine has gained a lot of interest due to its soothing and euphoric properties. Mitragynine is unique in the sense that it’s the primary active component in the kratom leaf and comprises up to two-thirds of the alkaloid content found in kratom. 

As kratom grows in popularity, mitragynine extraction has become common practice for its many properties. To understand more about kratom alkaloid content, it’s important to understand mitragynine. 

How Mitragynine Works

Mitragynine has been studied for its ability to act as a brain receptor agonist or antagonist. Mitragynine binds to receptors, giving it both sedative and stimulant effects. It also binds to serotonergic 5HT2A and 5HT7 receptors, adrenergic Alpha1B and beta2 receptors, histaminergic H1 receptors, all with low binding affinities. 

This kratom alkaloid is a great starting point to begin understanding the active compounds in kratom and their effects. By binding to different receptors, mitragynine gives kratom its known effects. Mitragynine is also responsible for stimulating the adrenergic receptors, which can give you a boost of energy and motivation when needed.

How Mitragynine is Extracted

Mitragynine extraction has become a go-to practice for kratom users who want more potent kratom. Considering it’s the most abundant alkaloid in kratom, mitragynine makes up a huge part of the popular kratom extracts that are on the market. It can be extracted using various solvents, but the most common include water extraction and alcohol extraction. The extraction can either be done by users using whole kratom leaf or by kratom product manufacturers. 

Extraction is not necessary for those who purchase kratom products, but it can significantly increase the alkaloid content of their preferred strain. You can buy mitragynine in its pure form to add to your regular kratom, or you could purchase mitragynine-rich extracts from a reputable kratom vendor. Mitragynine extraction methods have become more refined as researchers learn more about it, so mitragynine-rich kratom extracts are becoming more potent.

Mitragynine Studies Are Growing 

Like many other ethnobotanical plants, Mitragyna speciosa is being studied for its kratom alkaloid content. Mitragynine has gained a lot of scientific interest due to its psychoactive properties. While studies are just getting started, mitragynine has been found to be have strong soothing properties and may provide mild relief for day-to-day discomfort and help boost your mood. 


There’s a lot more to mitragynine than we know. The kratom plant has traditionally been used for hundreds of years as a remedy, so looking at mitragynine can help us understand how it works, its effects, and how to improve mitragynine extraction for better products that benefit our personal wellbeing. 

Learn More from Knowledgeable Industry Pros

Whether you’re just getting started with kratom or are a well-versed user, it’s important to understand the kratom alkaloid content in Mitragyna speciosa. The mitragynine alkaloid is believed to be responsible for most of the effects of kratom while also delivering subtle energy-boosting and mood-enhancing properties. Mitragynine alkaloid content varies depending on the origin of the Mitragyna speciosa leaves, growing conditions, and harvesting techniques.

That’s why getting your kratom from a reliable, reputable kratom supplier is so important. At The Kratom Company, we provide premium quality kratom with mitragynine levels carefully monitored to ensure consistency, potency, quality, and purity. For more information on mitragynine alkaloid and mitragynine extraction, get in touch with our trustworthy experts at The Kratom Company. 

Anthony Dent is one of the founders of The Kratom Company who has had years of personal and professional experience in the industry. As a kratom user himself, he is an advocate for all the potential benefits kratom can offer users both new and experienced. As the industry and legal atmosphere change, Anthony stays up to date on the latest Kratom Consumer Protection Acts to keep readers up to date with reliable information.
Anthony DentFounding Member

Leave a Reply

These statements and products presented on this website have not been evaluated by the Food and Drug Administration FDA. The products mentioned on this website are not intended to diagnose, prevent, treat or cure any diseases or health conditions. Therefore any information on this website is presented solely as the opinions of their respective authors who do not claim in any way shape or form to be medical professionals providing medical advice. The KRTM Company and its owners or employees cannot be held responsible for, and will not be liable for the inaccuracy or application of any information whatsoever herein provided. By purchasing our products you agree that you are aware and in compliance with your local county, state, or federal regulations. Must be 21 years or older to purchase Kratom. The US FDA has not approved kratom as a dietary supplement. We do not ship to the following states, cities and counties in the US where Kratom is banned: Alabama, Arkansas, Indiana, Rhode Island, Vermont, Wisconsin, Sarasota County, FL, Union County, MS, Denver, CO, San Diego, CA, and Jerseyville, IL.